Affymetrix, Inc. engages in the development, manufacture, sale, and servicing of consumables and systems for genetic analysis in the life sciences and clinical healthcare markets primarily in the United States, Europe, Japan. The company provides integrated GeneChip microarray platform, which includes disposable DNA probe arrays (chips) consisting of nucleic acid sequences, certain reagents for use with the probe arrays, a scanner and other instruments used to process the probe arrays, and software to analyze and manage genomic or genetic information obtained from the probe arrays. It also offers GeneTitan, an instrument system that runs genotyping and gene expression array plates; and GeneAtlas, an instrument for low-to-medium throughput that provides hybridization and array processing with microwell-based labware, as well as a line of multiplex assays to serve the discovery and the validation markets. In addition, the company provides reagent kits, including ExoSAP-IT for a reagent for the clean-up of polymerase chain reaction (PCR) products used in downstream applications, such as DNA sequencing or single-nucleotide polymorphisms analysis; and HotStart-IT reagents that utilize a novel primer binding protein to inhibit primer dimer formation with results in sensitive and consistent amplification for PCR. Its products are used primarily in genotyping and gene expression applications. The company sells its products directly to pharmaceutical, biotechnology, agrichemical, diagnostics, and consumer products companies; academic research centers, government research laboratories, private foundation laboratories, and clinical reference laboratories in North America and Europe, as well as through life science supply specialists acting as authorized distributors in Latin America, the Middle East, and Asia Pacific regions. Affymetrix, Inc. was founded in 1991 and is headquartered in Santa Clara, California.