Neuralstem, Inc., a biopharmaceutical company, focuses on the development and commercialization of regenerative medicine treatments based on its human neuronal stem cells and small molecule compounds. The company’s stem cell technology enables the isolation and expansion of human neural stem cells from various areas of the developing human brain and spinal cord enabling the generation of physiologically relevant human neurons of all types. Its clinical program products include NSI-566, which is in ongoing Phase II clinical trials for the treatment of amyotrophic lateral sclerosis, as well as in Phase I clinical trial for chronic spinal cord injury. The company’s clinical development products also comprise NSI–566 that is in Phase I/II clinical trials for motor deficits due to ischemic stroke in China; NSI–189 that completed Phase Ia and Ib trials for the treatment of major depressive disorders; and NSI–189, which is in Phase Ib preparation for cognitive deficit in schizophrenia. Neuralstem, Inc. was founded in 1996 and is headquartered in Germantown, Maryland.