Stock Report: Infinity Pharmaceuticals Inc. (INFI) Report Updated: Jun 17, 2013 | Print This Page

Infinity Pharmaceuticals, Inc., a drug discovery and development company, focuses on discovering, developing, and delivering medicines to patients for diseases with significant unmet need. The company’s lead product candidates include IPI-145, an inhibitor of the delta and gamma isoforms of phosphoinositide-3-kinase; Retaspimycin HCl, a heat shock protein 90 inhibitor; and IPI-940, an inhibitor of fatty acid amide hydrolase, which completed Phase 1 clinical trial. It is also pursuing a dual development path for IPI-145 in both hematologic malignancies and inflammation. The IPI-145 is in an ongoing, Phase 1 dose-escalation trial in patients with advanced hematologic malignancies and in a Phase 2a signal-finding study in patients with mild, allergic asthma. In addition, the company plans to initiate a Phase 2a signal-finding study in patients with rheumatoid arthritis. The Retaspimycin HCl is in a Phase 2 trial in combination with docetaxel to treat patients with non-small cell lung cancer (NSCLC); and in a Phase 1b/2 trial in combination with everolimus in approximately 45 NSCLC patients with a KRAS mutation. The company is headquartered in Cambridge, Massachusetts.