NxStage Medical, Inc., a medical device company, develops, manufactures, and markets products for the treatment of kidney failure, fluid overload, and related blood treatments and procedures. Its primary product, the NxStage System One, is a portable hemodialysis system used for home hemodialysis and a range of dialysis therapies for chronic home hemodialysis treatment, and the treatment of acute kidney failure and fluid overload. The NxStage System One comprises components, such as The NxStage Cycler, a compact portable electromechanical device; The NxStage Cartridge, a single-use integrated treatment cartridge; and premixed dialysate for hemodialysis applications. The company also sells a line of extracorporeal disposable products for use primarily for in-center dialysis treatments for patients with end-stage renal disease (ESRD); and needles and blood tubing sets primarily to dialysis clinics for the treatment of ESRD. NxStage Medical, Inc. markets its products primarily to dialysis clinics, nephrologists, and hospitals through distributors and sales representatives in the United States, Mexico, and Europe. The company was formerly known as QB Medical, Inc. and changed its name to NxStage Medical, Inc. NxStage Medical, Inc. founded in 1998 and is headquartered in Lawrence, Massachusetts.